Can a single dose response predict the effect of montelukast on exercise-induced bronchoconstriction?

Research output: Contribution to journalArticle


Exercise-induced bronchoconstriction (EIB) can be prevented by a single dose of montelukast (MLK). The effect is variable, similar to the variable responsiveness observed after daily treatment with MLK. We hypothesized that the effect of a single MLK-dose (5 or 10 mg) on EIB could predict the clinical effectiveness of longer term once daily treatment.


  • Elin T G Kersten
  • Anne M Akkerman-Nijland
  • Jean M M Driessen
  • Zuzana Diamant
  • Bernard J Thio
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Respiratory Medicine and Allergy
Original languageEnglish
JournalPediatric Pulmonology
Early online date2015 Oct 22
Publication statusPublished - 2015
Publication categoryResearch