CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice.

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Abstract

It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully characterized. In the present study we assessed immune responses to hypercholesterolemia induced by feeding Apoe-/- mice a high-fat diet for 4 or 8 weeks.

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  • Immunology in the medical area
Original languageEnglish
Article number58
JournalBMC Immunology
Volume11
Publication statusPublished - 2010
Publication categoryResearch
Peer-reviewedYes

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