CDKN2A-mutation hos en familie med arveligt malignt melanom
Research output: Contribution to journal › Article
Malignant melanoma (MM) is a frequent form of cancer with increasing incidence. 6-10% of patients with MM report a family history of MM, and in most populations 2% of unselected cases of MM carry a CDKN2A mutation. tvWe present a family with 24 cases of MM in nine persons from several generations, caused by a previously undescribed germ-line intronic mutation in CDKN2A. Through genetic counselling and genetic testing high-risk persons in the family are located and offered regular screening for MM.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Translated title of the contribution||CDKN2A-mutation in a family with hereditary malignant melanoma|
|Journal||Ugeskrift for Laeger|
|Publication status||Published - 2014 Sep 29|