CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.

Research output: Contribution to journalArticle

Abstract

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to the disease cystic fibrosis (CF). Although patients with CF often have disturbances in glucose metabolism including impaired insulin release, no previous studies have tested the hypothesis that CFTR has a biological function in pancreatic beta-cells.

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Subject classification (UKÄ) – MANDATORY

  • Endocrinology and Diabetes
Original languageEnglish
Article number87
JournalBMC Medicine
Volume12
Issue number1
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes

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Related research output

Anna Edlund, 2016, 150 ed. Lund: Lund University, Faculty of Medicine. 69 p.

Research output: ThesisDoctoral Thesis (compilation)

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