Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's disease: An international multicenter study.
Research output: Contribution to journal › Article
The characteristic off periods that develop over time in subjects with Parkinson's disease (PD) on chronic levodopa therapy are usually considered to be motor complications but more recently the important contribution of non-motor off and non-motor fluctuations has also been acknowledged. Early-morning off (EMO) periods in PD patients are known to be a cause of significant disability, in addition to having a negative impact on quality of life. Yet EMOs are poorly defined, particularly in relation to non-motor symptoms (NMS).
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Parkinsonism & Related Disorders|
|Publication status||Published - 2014|