Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

Research output: Contribution to journalArticle

Abstract

The relationship between tumour necrosis factor-alpha (TNF-α) and drug survival had not been studied in juvenile idiopathic arthritis (JIA) and there were no laboratory tests to predict the long-term efficacy of biological drugs for JIA. We studied if serum levels of TNF-α, free or bound to etanercept, could predict long-term efficacy of etanercept in children with JIA.

Details

Authors
Organisations
External organisations
  • Lund University
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Rheumatology and Autoimmunity
  • Pediatrics
Original languageEnglish
Pages (from-to)427-432
JournalActa paediatrica
Volume105
Issue number4
Early online date2015 Dec 27
Publication statusPublished - 2016
Publication categoryResearch
Peer-reviewedYes