Clinical Application of Fusion Gene Detection Using Next-Generation Sequencing and the NanoString Technology

Research output: Contribution to journalArticle

Abstract

Fusion gene detection is of great diagnostic value since the presence of fusion genes may dictate treatment and patient outcome. When detecting fusion genes in clinical samples there are multiple aspects to consider regarding sample origin, choice of fusion gene detection technique, and data analysis.

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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Genetics
  • Cancer and Oncology

Keywords

  • FFPE, Fusion gene, NanoString, Next-generation sequencing, RNA, Targeted RNA sequencing
Original languageEnglish
Pages (from-to)139-152
Number of pages14
JournalMethods in molecular biology (Clifton, N.J.)
Volume1908
Publication statusPublished - 2019
Publication categoryResearch
Peer-reviewedYes