Clinical course in synovial sarcoma: A Scandinavian sarcoma group study of 104 patients

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We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.


  • Björn T. Skytting
  • Henrik C.F. Bauer
  • Roland Perfekt
  • Riika Huuhtanen
  • Thor A. Alvegârd
  • Örjan Berlin
  • Pelle Gustafson
  • Ragnhild Klepp
  • Richard Löfvenberg
  • Gunnar Seter
  • Clement S. Trovik
  • Ola Wahlström
External organisations
  • Södersjukhuset
  • Karolinska University Hospital
  • Helsinki University Central Hospital
  • Sahlgrenska University Hospital
  • St. Olav’s University Hospital
  • Norrland University Hospital
  • Norwegian Radium Hospital
  • Haukeland University Hospital
  • Linköping University Hospital
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Orthopedics
  • Cancer and Oncology
Original languageEnglish
Pages (from-to)536-542
JournalActa Orthopaedica Scandinavica
Issue number6
Publication statusPublished - 1999
Publication categoryResearch