Comparison between transcranial Doppler and coulter counter for detection of lipid micro embolization from mediastinal shed blood reinfusion during cardiac surgery.

Research output: Contribution to journalArticle


INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P<0.005). CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery.


Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Surgery
  • Cardiac and Cardiovascular Systems
Original languageEnglish
Pages (from-to)519-523
Issue number5
Publication statusPublished - 2011
Publication categoryResearch

Related research output

Eyjolfsson, A., 2011, Department of Cardiothoracic Surgery, Clinical Sciences, Lund University. 132 p.

Research output: ThesisDoctoral Thesis (compilation)

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