Computational Perspectives on Neuromodulation of Aging
Research output: Contribution to journal › Review article
Cognitive functions, such as memory, attention, and perception, declines with age. Besides other neuroanatomical changes, the level of dopamine also attenuates during aging. We review how computational modeling can provide insights in how these lifetime changes in dopamine levels is expressed at the behavioral level yielding a bridge across different levels. Results indicate that attenuation of dopamine lowers the signal to noise ratio providing a less distinctive neural representation, and detrimental cognitive performance.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Acta Neurochirurgica. Supplementum|
|Publication status||Published - 2007|