Computer simulation analysis of source-detector position for percutaneously measured O2-gas signal in a three-dimensional preterm infant lung

Research output: Contribution to journalArticle


Further improvements in the clinical care of our most vulnerable patients-preterm infants-are needed. Novel diagnostic and surveillance tools facilitate such advances. The GASMAS technique has shown potential to become a tool to, noninvasively, monitor gas in the lungs of preterm infants, by placing a laser source and a detector on the chest wall skin. It is believed that this technology will become a valuable clinical diagnostic tool for monitoring the lung function of these patients. Today, the technology is, for this application, in an early stage and further investigations are needed. In the present study, a three-dimensional computer model of the thorax of an infant is constructed, from a set of CT images. Light transport simulations are performed to provide information about the position dependence of the laser- and detector probe on the thorax of the infant. The result of the simulations, based on the study method and the specified model used in this work, indicates that measurement geometries in front and on the side of the lung are favorable in order to obtain a good gas absorption signal.


External organisations
  • Skåne University Hospital
  • Tyndall National Institute
  • University College Cork
  • GPX Medical AB
  • Lund University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Equipment Engineering


  • Computational phantom, Light transport simulation, Preterm infants, Respiratory distress syndrome, Tunable diode laser absorption spectroscopy
Original languageEnglish
Article numbere201800023
JournalJournal of Biophotonics
Issue number11
Early online date2018 Jul 5
Publication statusPublished - 2018
Publication categoryResearch