Concise Total Synthesis of Dehaloperophoramidine.

Research output: Contribution to journalArticle

Abstract

Perophoramidine, dehaloperophoramidine, and communesin F are structurally related alkaloids having intriguing polycyclic structures. A strategy for the synthesis of dehaloperophoramidine has been developed. In this synthesis all skeletal atoms and all functional groups required to reach the target molecule are incorporated early in the sequence. This approach led to the discovery of two novel substrate-specific domino processes, one encompassing four steps and the other comprising five steps, thus resulting in an eight-step synthesis of dehaloperophoramidine.

Details

Authors
Organisations
External organisations
  • University of Tartu
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry
Original languageEnglish
JournalAngewandte Chemie (International edition)
Early online date2015 Dec 16
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

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