Consumption of meat and fish and risk of lung cancer: results from the European Prospective Investigation into Cancer and Nutrition

Research output: Contribution to journalArticle

Abstract

Evidence from case-control studies, but less so from cohort studies, suggests a positive association between meat intake and risk of lung cancer. Therefore, this association was evaluated in the frame of the European Prospective Investigation into Cancer and Nutrition, EPIC. Data from 478,021 participants, recruited from 10 European countries, who completed a dietary questionnaire in 1992-2000 were evaluated; 1,822 incident primary lung cancer cases were included in the present evaluation. Relative risk estimates were calculated for categories of meat intake using multi-variably adjusted Cox proportional hazard models. In addition, the continuous intake variables were calibrated by means of 24-h diet recall data to account for part of the measurement error. There were no consistent associations between meat consumption and the risk of lung cancer. Neither red meat (RR = 1.06, 95% CI 0.89-1.27 per 50 g intake/day; calibrated model) nor processed meat (RR = 1.13, 95% CI 0.95-1.34 per 50 g/day; calibrated model) was significantly related to an increased risk of lung cancer. Also, consumption of white meat and fish was not associated with the risk of lung cancer. These findings do not support the hypothesis that a high intake of red and processed meat is a risk factor for lung cancer.

Details

Authors
  • Jakob Linseisen
  • Sabine Rohrmann
  • Bas Bueno-de-Mesquita
  • Frederike L. Buchner
  • Hendriek C. Boshuizen
  • Antonio Agudo
  • Inger Torhild Gram
  • Christina C. Dahm
  • Kim Overvad
  • Rikke Egeberg
  • Anne Tjonneland
  • Heiner Boeing
  • Annika Steffen
  • Rudolf Kaaks
  • Annekatrin Lukanova
  • Franco Berrino
  • Domenico Palli
  • Salvatore Panico
  • Rosario Tumino
  • Eva Ardanaz
  • Miren Dorronsoro
  • Jose-Maria Huerta
  • Laudina Rodriguez
  • Maria-Jose Sanchez
  • Torgny Rasmuson
  • Goran Hallmans
  • Dagrun Engeset
  • Guri Skeie
  • Michael Katsoulis
  • Eleni Oikonomou
  • Antonia Trichopoulou
  • Petra H. M. Peeters
  • Kay-Tee Khaw
  • Nicholas Wareham
  • Naomi Allen
  • Tim Key
  • Paul Brennan
  • Isabelle Romieu
  • Nadia Slimani
  • Anne-Claire Vergnaud
  • Wei W. Xun
  • Paolo Vineis
  • Elio Riboli
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology

Keywords

  • Lung cancer, Diet, Epidemiology, Meat, Fish, EPIC
Original languageEnglish
Pages (from-to)909-918
JournalCancer Causes and Control
Volume22
Issue number6
Publication statusPublished - 2011
Publication categoryResearch
Peer-reviewedYes