Contribution of plasma-derived molecules to mucosal immune defence, disease and repair in the airways

Research output: Contribution to journalReview article

Abstract

This review discusses recent observations, in health and disease, on the release and distribution of plasma-derived molecules in the airway mucosa. Briefly, the new data on airway mucosal exudation mechanisms suggest that the protein systems of plasma contribute significantly to the mucosal biology, not only in injured airways but also in such mildly inflamed airways that lack oedema and exhibit no sign of epithelial derangement. Plasma as a source of pluripotent growth factor, adhesive, leucocyte-activating, etc., molecules may deserve a prominent position in schemes that claim to illustrate immunological and inflammatory mechanisms of the airway mucosa in vivo.

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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Immunology in the medical area
Original languageEnglish
Pages (from-to)302-313
JournalScandinavian Journal of Immunology
Volume47
Issue number4
Publication statusPublished - 1998
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Airway Inflammation and Immunology (013212038), Neuroendocrine Cell Biology (013212008), Division of Clinical Chemistry and Pharmacology (013250300), Otorhinolaryngology (Lund) (013044000)