Correlation between dominant EEG frequency, cerebral oxygen uptake and blood flow

Research output: Contribution to journalArticle

Abstract

In 32 chronic patients the EEG in temporal and occipito-parietal bipolar leads was analyzed with a manual method giving a period frequency index. The cerebral oxygen uptake (CMRO2) was calculated from the arteriovenous oxygen difference between samples from the internal carotid artery and the jugular bulb respectively, and from measurement of cerebral blood flow with the 133Xenon clearance method. A strong correlation (r = 0.78, P < 0.001) was found between the EEG frequency indices and the CMRO2 of the hemisphere from which the EEG was recorded. Significant correlations between the EEG indices and gray matter cerebral blood flow were also demonstrated, while the correlation between the EEG indices and the blood flow of the white matter was weak. No correlation at all was found between the EEG indices and the relative weight of the gray matter. We conclude that the EEG carries information about the metabolic activity of the brain tissue. The EEG frequency also correlates with the blood flow of the gray matter of the brain when tissue anoxia has not uncoupled the normal function—flow relationship prevailing in the brain.

Details

Authors
  • D. H. Ingvar
  • B. Sjölund
  • Anders Ardö
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Neurology
Original languageEnglish
Pages (from-to)268-276
JournalClinical Neurophysiology
Volume41
Issue number3
Publication statusPublished - 1976
Publication categoryResearch
Peer-reviewedYes