Critical review of current definitions of urinary tract infections and proposal of an EAU/ESIU classification system

Research output: Contribution to journalReview article


Classification of urinary tract infections (UTI) is important for clinical decisions, research, quality measurement and teaching. Current definitions of UTI are above all based on the concept of the two main categories, complicated and uncomplicated UTI. The category "complicated UTI" especially is very heterogeneous and not always clear. We propose the EAU/ESIU classification system ORENUC based on the clinical presentation of the UTI, categorisation of risk factors and availability of appropriate antimicrobial therapy, which finally may result in the definition of UTI severity groups. (C) 2011 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved.


  • Truls E. Bjerklund Johansen
  • Henry Botto
  • Mete Cek
  • Magnus Grabe
  • Peter Tenke
  • Florian M. E. Wagenlehner
  • Kurt G. Naber
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Pharmacology and Toxicology


  • Classification, Urinary tract infection, Cystitis, Pyelonephritis, Urosepsis, Risk factors
Original languageEnglish
Pages (from-to)64-70
JournalInternational Journal of Antimicrobial Agents
Issue numberSuppl.
Publication statusPublished - 2011
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Urology (013243400), Pediatrics/Urology/Gynecology/Endocrinology (013240400)