Cross-vendor transfer and RF coil comparison of a high-resolution MP2RAGE protocol for brain imaging at 7T

Research output: Contribution to journalArticle


Abstract. An established MP2RAGE protocol for semi-quantitative structural brain MRI was transferred from one 7T MR scanner to that of another vendor featuring comparable hardware, but opposite polarity. On this system, the scan time could be reduced from 11 to 8 minutes by elliptical k-space sampling. Three configurations of radio-frequency (RF) transmission were compared (single channel with quadrature slitting, two and eight channels of fixed phase delays). Data processing for offline calculation MP2RAGE images is described in detail. The DICOM scaling of scanner B entails a loss of precision and accuracy and stronger artifacts in regions of low RF field, which can be improved by dielectric pads. For comparison and multi-site studies, though, use of an identical scan protocol and identical RF hardware is recommended.


External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging


  • quantitative MRI, structural imagin, T1 relaxatio, brai, ultra-high field, signal scaling
Original languageEnglish
Article number2020-001
Pages (from-to)1-12
JournalActa Scientiarum Lundensia
Issue number001
Publication statusPublished - 2020 May 12
Publication categoryResearch
EventWorking paper in UHF MRI methods -
Duration: 2020 May 12 → …

Bibliographic note

G.H. was funded by Swedish Research Council (NT 2014-6193). The reference MP2RAGE protocol was kindly provided by Dr. Robert Trampel, Max-Planck-Institute for Human Cognition and Brain Sciences, Leipzig, Germany. Lund University Bioimaging Center (LBIC) is acknowledged for experimental resources (equipment grant VR RFI 829-2010-5928). Reviewer: Benedikt Poser, Maastricht University,

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