Cubosomes for ruthenium complex delivery: formulation and characterization

Research output: Contribution to journalArticle

Abstract

An amphiphilic ruthenium-based molecule (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.

Details

Authors
  • Gaetano Mangiapia
  • Mauro Vaccaro
  • Gerardino D'Errico
  • Henrich Frielinghaus
  • Aurel Radulescu
  • Vitaliy Pipich
  • Anna Carnerup
  • Luigi Paduano
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Physical Chemistry
Original languageEnglish
Pages (from-to)10577-10580
JournalSoft Matter
Volume7
Issue number22
Publication statusPublished - 2011
Publication categoryResearch
Peer-reviewedYes