Current methods for absorbed dose planning for radioiodine treatment of hyperthyroidism in Sweden

Research output: Contribution to journalArticle


Radioiodine therapy is a common form for treatment of hyperthyroidism. This treatment has been performed for half a century, with the annual number of I-131-iodide therapies for hyperthyroidism in Sweden being around 3000 since the 1970s. Methods used to calculate the administered activity to the individual patient differ widely, and a survey was made to get information about the different protocols currently used in 23 hospitals in Sweden, which administer radioiodide for therapy of hyperthyroidism. Eighteen hospitals calculate the activity to be administered for a prescribed absorbed dose to the thyroid. The calculations of the activity to administer consider individual parameters such as the active volume of the thyroid and its uptake of I-131-iodide, but only 9 of the 18 hospitals consider the individual biological half time of I-131 in the thyroid. Five hospitals do not consider any individual biokinetic parameter or volume and prescribe just the activity to be administered. In total, 17 different protocols are used, and the investigation clearly illustrates the need to converge and optimize the radioiodine therapy in Sweden.


Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging


  • absorbed dose, hyperthyroidism, radioiodine, therapy
Original languageEnglish
Pages (from-to)99-103
JournalPhysica Medica
Issue number3
Publication statusPublished - 2004
Publication categoryResearch