Cytogenetic abnormalities in a hemangiopericytoma of the spleen.
Research output: Contribution to journal › Article
To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid and breakpoints in 12q13, 12q24, and 19q13 seem to be common, with t(12;19)(q13;q13) being a recurrent translocation. Here, we report the first case of a probably benign splenic HP with chromosomal abnormalities. The abnormal karyotype was 47,XX,t(5;22;11)(q31;q11;q13),+10. None of these abnormalities have previously been reported in HP, suggesting that the karyotypic pattern of splenic HP may differ from soft tissue HP.
|Research areas and keywords||
Subject classification (UKÄ)
|Journal||Cancer Genetics and Cytogenetics|
|Publication status||Published - 2002|
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Surgery (Lund) (013009000), Division of Clinical Genetics (013022003), Pathology, (Lund) (013030000), Surgery Research Unit (013242220)