Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
Research output: Contribution to journal › Article
Abstract
Kluth et al. identify a significant enrichment of cilia-annotated genes that are differentially expressed in pancreatic islets of obese mice. Many of the genes were also linked to human T2D, suggesting that dysregulation of cilia-associated genes may participate in T2D risk.
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Research areas and keywords | Subject classification (UKÄ) – MANDATORY
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Original language | English |
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Pages (from-to) | 3027-3036.e3 |
Journal | Cell Reports |
Volume | 26 |
Issue number | 11 |
Publication status | Published - 2019 |
Publication category | Research |
Peer-reviewed | Yes |