Delayed cochlear implantation in post-meningitic deafness and hereditary complement C2 deficiency

Research output: Contribution to journalArticle


We report the case of an adolescent with post-verbal severe/profound sensorineural hearing loss, occurring as a consequence of two bouts of pneumococcal meningitis at 12 and 32 months of age. A possible immunodeficiency was investigated, revealing hereditary complement C2 deficiency (C2D). Given the insufficient benefit from high-power hearing aids, the boy received a cochlear implant (CI) at age 12. Despite the long interval of partial hearing deprivation and the post-meningitic etiology, improvement in open-set speech perception and quality of life were observed. The C2D did not favour post-operative infections nor meningitis recurrence. The risks and benefit of CI in this peculiar clinical circumstance are discussed after reviewing the literature.


External organisations
  • University of Milan
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Otorhinolaryngology


  • Adolescence, C2, Cochlear implantation, Complement deficiency, Immunological, Meningitis
Original languageEnglish
Pages (from-to)4-8
Number of pages5
JournalInternational Journal of Pediatric Otorhinolaryngology Extra
Publication statusPublished - 2017 Jan 1
Publication categoryResearch