Development of a disease-specific quality of life questionnaire for children & adolescents with idiopathic thrombocytopenic purpura (ITP-QoL)

Research output: Contribution to journalArticle


Quality of life (QoL) assessment in children with coagulation disorders is a relatively unstudied area. While hemophilia-specific questionnaires (such as Haemo-QoL) are available, no instrument for children with idiopathic thrombocytopenic purpura (ITP) has been validated yet. A disease-specific questionnaire for children with ITP was therefore developed (ITP-QoL) in three phases: (a) a preparatory phase; (b) a developmental phase; (c) a pilot testing phase. Since dimensions of Haemo-QoL were considered important for children with ITP, items were adapted, reformulated and additional dimensions were included. Two age-group versions were designed for children (aged 3-7, 8-18 years) and parents in Italian, German, and Swedish languages and were pilot tested. Pediatr Blood Cancer 2006;47:688-691. (c) 2006 Wiley-Liss, Inc.


  • S. von Mackensen
  • Cecilia Nilsson
  • M. Jankovic
  • N. Mirra
  • E. D'Angelo
  • A. Borkhardt
  • Rolf Ljung
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Pediatrics


  • children, ITP, quality of life
Original languageEnglish
Pages (from-to)688-691
JournalPediatric Blood & Cancer
Issue numberSuppl.5
Publication statusPublished - 2006
Publication categoryResearch