Diels-Alder adducts derived from the natural phthalide Z-ligustilide

Research output: Contribution to journalArticle

Abstract

Z-Ligustilide, a naturally occurring phthalide isolated from Ligusticum porteri, underwent Diels-Alder reactions with different dienophiles yielding novel tricyclic products with potentially interesting biological properties. Where selectivity was possible, the reactions performed showed regio- and stereoselectivity. The experimental results with ethyl acrylate were compared with the selectivity predicted by ab initio calculations.

Details

Authors
  • Erik Lager
  • Anders Sundin
  • Ruben A. Toscano
  • Guillermo Delgado
  • Olov Sterner
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry

Keywords

  • STAT3, Z-ligustilide, galiellalactone, ab initio, Diels-Alder
Original languageEnglish
Pages (from-to)4215-4218
JournalTetrahedron Letters
Volume48
Issue number24
Publication statusPublished - 2007
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)