Diffusion MRI and Poroelastic Biomechanics of Articular Cartilage

Research output: Chapter in Book/Report/Conference proceedingBook chapter

Abstract

Cartilage is a poroelastic material for which application of load leads to fluid flow within and out from the porous solid matrix. The redistribution of fluids is a major factor in determining the mechanical properties and friction coefficients, which consequently depend in a complex way on the details of the load history and geometry. Although current poroelastic models for cartilage generally agree with the observed macroscopic behavior, critical tests of the underlying assumptions require direct measurements of the translational motion of the pore fluids. This chapter reviews magnetic resonance imaging investigations of water diffusion and flow in cartilage, with special emphasis on time-resolved measurements during dynamic loading.

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Subject classification (UKÄ) – MANDATORY

  • Biophysics
Original languageEnglish
Title of host publicationBiophysics and Biochemistry of Cartilage by NMR and MRI
PublisherRoyal Society of Chemistry
Pages375-394
Number of pages20
Volume2017-January
Edition8
Publication statusPublished - 2017
Publication categoryResearch
Peer-reviewedYes

Publication series

NameNew Developments in NMR
Number8
Volume2017-January
ISSN (Print)2044253X
ISSN (Electronic)20442548