Disease models of chronic inflammatory airway disease: applications and requirements for clinical trials.
Research output: Contribution to journal › Review article
This review will discuss methodologies and applicability of key inflammatory models of respiratory disease in proof of concept or proof of efficacy clinical studies. In close relationship with these models, induced sputum and inflammatory cell counts will be addressed for phenotype-directed drug development. Additionally, important regulatory aspects regarding noninvestigational medicinal products used in bronchial challenges or clinical inflammatory models of respiratory disease will be highlighted.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Current Opinion in Pulmonary Medicine|
|Publication status||Published - 2014|