Does next-generation sequencing of cyst fluid improve management of pancreatic cystic neoplasms?

Research output: Contribution to journalReview article

Abstract

Pancreatic cystic lesions represent a heterogeneous group of diseases ranging from benign to malignant lesions. They are increasingly being detected due to the widespread use of cross-sectional imaging. Their management is a challenge because it is often not possible to reliably discriminate between malignant and nonmalignant lesions using current imaging technology. Next-generation sequencing (NGS) has the ability of both whole genome and targeted sequencing at a low cost and from a limited amount of DNA. NGS of cyst fluid aspired by endoscopic ultrasonography-guided fine-needle aspiration provides a valuable tool in biomarker research and may in the future help improve diagnosis and management of pancreatic cystic lesions.

Details

Authors
Organisations
External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Bioinformatics and Systems Biology

Keywords

  • biomarker, cyst fluid, next-generation sequencing, Pancreatic cystic lesions
Original languageEnglish
Pages (from-to)1049-1051
Number of pages3
JournalScandinavian Journal of Gastroenterology
Volume52
Issue number10
Publication statusPublished - 2017 Oct 3
Publication categoryResearch
Peer-reviewedYes