Drug delivery to retinal photoreceptors

Research output: Contribution to journalReview article

Abstract

The photoreceptors of the retina are afflicted by diseases that still often lack satisfactory treatment options. Although suitable drugs might be available in some cases, the delivery of these compounds into the eye and across the blood–retinal barrier remains a significant challenge for therapy development. Here, we review the routes of drug administration to the retina and highlight different options for drug delivery to the photoreceptor cells.

Details

Authors
  • Erico Himawan
  • Per Ekström
  • Matej Buzgo
  • Pieter Gaillard
  • Einar Stefánsson
  • Valeria Marigo
  • Thorsteinn Loftsson
  • François Paquet-Durand
Organisations
External organisations
  • University of Iceland
  • University of Modena and Reggio Emilia
  • University of Tübingen
  • Inocure SRO
  • 2-BBB Medicines BV
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Ophthalmology
Original languageEnglish
Pages (from-to)1637-1643
JournalDrug Discovery Today
Volume24
Issue number8
Early online date2019
Publication statusPublished - 2019
Publication categoryResearch
Peer-reviewedYes