Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.

Research output: Contribution to journalArticle

Abstract

Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.

Details

Authors
Organisations
External organisations
  • Leiden University Medical Centre
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging
Original languageEnglish
Pages (from-to)996-1006
JournalMagnetic Resonance in Medicine
Volume72
Issue number4
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes

Related research output

Emelie Lind, 2019 Feb, Lund: Naturvetenskapliga fakulteten, Lunds universitet. 181 p.

Research output: ThesisDoctoral Thesis (compilation)

View all (1)

Related projects

View all (1)