Eculizumab in an anephric patient with atypical haemolytic uraemic syndrome and advanced vascular lesions.

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Abstract

Atypical haemolytic uraemic syndrome (aHUS) is associated with dysfunction of the alternative pathway of complement. Disease activity subsides as renal failure progresses but recurs upon renal transplantation, indicating that viable renal tissue contributes to disease activity. We present evidence of cerebrovascular occlusive disease indicating that vascular injury may occur in the absence of kidneys.

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Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging
  • Pediatrics
Original languageEnglish
Pages (from-to)2899-2907
JournalNephrology Dialysis Transplantation
Volume28
Issue number11
Publication statusPublished - 2013
Publication categoryResearch
Peer-reviewedYes

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