Effect of gel-instillation sonography on Doppler ultrasound findings in endometrial polyps

Research output: Contribution to journalArticle


Objective Saline infusion sonohysterography has been reported to suppress the color signal within the endometrium at color or power Doppler evaluation. The aim of this study was to evaluate if gel-instillation sonography (GIS) affects the power Doppler signal in patients with endometrial polyps. Methods Ultrasound volumes of the uterus, obtained by three-dimensional ultrasound imaging of 25 women with histologically confirmed endometrial polyps, were assessed offline by six gynecologists with a special interest in gynecological ultrasound. Each woman contributed four volumes: one gray-scale volume and one power Doppler volume before GIS, and one gray-scale volume and one power Doppler volume at GIS. Power Doppler features before and after gel infusion were compared. Results At unenhanced ultrasound a pedicle artery was seen in 27-46% of cases, whereas, after gel infusion the examiners reported a pedicle artery in 30-46% of cases (Exact McNemar's test P-values ranged from 0.50 to 1.00). The level of agreement between unenhanced ultrasound and GIS ranged from 59 to 91% (Cohen's kappa values ranged from 0.17 to 0.79). There was no tendency for a pedicle artery to be identified less often at GIS than before gel instillation. Conclusion Gel infusion does not affect the power Doppler signal in patients with endometrial polyps. Copyright. (C) 2011 ISUOG. Published by John Wiley & Sons, Ltd.


  • T. Van den Bosch
  • D. Van Schoubroeck
  • J. Luts
  • T. Bignardi
  • G. Condous
  • Elisabeth Epstein
  • F. P. Leone
  • A. C. Testa
  • Lil Valentin
  • S. Van Huffel
  • T. Bourne
  • D. Timmerman
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging


  • Doppler ultrasound, endometrial polyp, gel-infusion sonography, three-dimensional imaging, ultrasonography
Original languageEnglish
Pages (from-to)355-359
JournalUltrasound in Obstetrics & Gynecology
Issue number3
Publication statusPublished - 2011
Publication categoryResearch