Effect of hyperthermia and/or nicotinamide on the radiation response of a C3H mammary carcinoma

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Abstract

The effect of hyperthermia and/or nicotinamide (200 mg/kg of body weight) on the tumour growth delay induced by radiation was evaluated in a C3H mouse mammary adenocarcinoma. The study showed a radiosensitizing effect of hyperthermia and of nicotinamide but the combination of all three modalitites showed no increased tumor growth delay compared to hyperthermia and radiation alone. The tumour growth delay induced by hyperthermia was not modified by nicotinamide.

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Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology
  • Immunology in the medical area
  • Radiology, Nuclear Medicine and Medical Imaging
Original languageEnglish
Pages (from-to)1733-1737
JournalEuropean journal of cancer & clinical oncology
Volume25
Issue number12
Publication statusPublished - 1989
Publication categoryResearch
Peer-reviewedYes