Effect of treatments on the progression of COPD: report of a workshop held in Leuven, 11-12 March 2004

Research output: Contribution to journalReview article


During the last decade several long term studies of interventions in patients with COPD have been published. This review analyses the potential of these interventions to alter the progression of the condition. The only treatment that has unequivocally been shown to reduce the rate of decline in FEV(1) is smoking cessation. Active psychological intervention in combination with pharmacotherapy is required. Other treatments may have an effect on the rate of decline in FEV(1) but this appears to be very small, at most. Several treatments affect the exacerbation rate and therefore might affect the progression of the disease. Further studies are warranted to examine this effect.


  • M Decramer
  • R Gosselink
  • P Bartsch
  • Claes-Göran Löfdahl
  • W Vincken
  • R Dekhuijzen
  • J Vestbo
  • R Pauwels
  • R Naeije
  • T Troosters
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Respiratory Medicine and Allergy


  • chronic obstructive pulmonary disease, progression, smoking cessation, treatment, rehabilitation
Original languageEnglish
Pages (from-to)343-349
Issue number4
Publication statusPublished - 2005
Publication categoryResearch