Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform.

Research output: Contribution to journalArticle

Abstract

Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated a novel microchip-based acoustophoresis technique, utilizing ultrasonic standing wave forces for the removal of platelets from PBPC products. By applying an acoustic standing wave field onto a continuously flowing cell suspension in a micro channel, cells can be separated from the surrounding media depending on their physical properties.

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Subject classification (UKÄ) – MANDATORY

  • Cell and Molecular Biology
  • Hematology
Original languageEnglish
Article numbere23074
JournalPLoS ONE
Volume6
Issue number8
Publication statusPublished - 2011
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Hematology and Transfusion Medicine (013041100), Stem Cell Center (013022011), Biomedical Engineering (011200011), Hematopoietic Stem Cell Laboratory (013022012), Hematology/Transplantation (013022014)

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Related research output

Dykes, J., 2013, Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University. 166 p.

Research output: ThesisDoctoral Thesis (compilation)

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