Enkephalin-immunoreactive cells in the mesencephalic tegmentum project to the optic tectum of the teleosts Salmo gairdneri and Salmo salar

Research output: Contribution to journalArticle

Abstract

Immunocytochemistry using antibodies against Met-enkephalin and Leu-enkephalin has demonstrated a group of large enkephalin-immunoreactive neurons in the nucleus of the rostral mesencephalic tegmentum (mRMT) of two teleost fish, Salmo gairdneri and Salmo salar. Injections of cobalt-lysine in the medial optic tectum retrogradely labeled the above group of tegmental neurons. Tegmental neurons were labeled only ipsilaterally to the injection site. This indicates that enkephalinergic neurons in the nRMT project to the optic tectum, and that at least some of the enkephalinergic axons observed in the optic tectum belong to a tegmento-tectal pathway. Comparable enkephalinergic pathways have been described in reptiles and birds, where pretectal-mesencephalic nuclei contribute to the enkephalin-containing fibers that project to the optic tectum.

Details

Authors
Organisations
External organisations
  • University of Salamanca
  • New York Medical College
Research areas and keywords

Keywords

  • Cobalt-lysine, Enkephalins, Immunocytochemistry, Retrograde labeling, Salmo gairdneri, Salmo salar (Teleostei), Tectum opticum, Tegmentum mesencephali
Original languageEnglish
Pages (from-to)133-137
Number of pages5
JournalCell and Tissue Research
Volume264
Issue number1
Publication statusPublished - 1991 Apr 1
Publication categoryResearch
Peer-reviewedYes