European task force on atopic dermatitis position paper: treatment of parental atopic dermatitis during preconception, pregnancy and lactation period

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Atopic dermatitis (AD) is a common inflammatory skin disease that affects both children and adults, including a large number of adults of reproductive age. Several guidelines for the treatment of AD exist, yet specific recommendations for the treatment of pregnant or lactating women and for adults planning to have a child are often lacking. This position paper from the European Task force on Atopic Dermatitis (ETFAD) is based on up-to-date scientific literature on treating pregnant and lactating women as wells as adults with AD planning to have a child. It is based on the expert opinions of members of the ETFAD and on existing safety data on the proposed treatments, many of which are derived from patients with other inflammatory diseases or from transplantation medicine. For treating future parents, as well as pregnant and lactating women with AD, the use of topical treatments including moisturizers, topical corticosteroids, tacrolimus, antiseptics such as chlorhexidine, octenidine, potassium permanganate and sodium hypochlorite (bleach) is deemed to be safe. Ultraviolet (UV) therapy may also be used. Systemic treatment should be prescribed only after careful consideration. According to the opinion of the ETFAD, treatment should be restricted to systemic corticosteroids and cyclosporine A, and, in selected cases, azathioprine.


  • C. Vestergaard
  • A. Wollenberg
  • S. Barbarot
  • S. Christen-Zaech
  • M. Deleuran
  • P. Spuls
  • C. Flohr
  • M. Trzeciak
  • J. Seneschal
  • C. Paul
  • T. Bieber
  • T. Werfel
  • R. Fölster-Holst
  • U. Darsow
  • U. Gieler
  • M. Cork
  • J. F. Stalder
  • L. De Raeve
  • B. Kunz
  • D. Simon
  • P. Chernyshov
  • D. Hijnen
  • C. Gelmetti
  • J. Ring
  • A. Taieb
  • M. de Bruin-Weller
  • J. P. Thyssen
External organisations
  • Aarhus University Hospital
  • Staedtisches Klinikum Muenchen
  • Nantes University Hospital
  • Lausanne University Hospital
  • Academic Medical Center of University of Amsterdam (AMC)
  • Guy's and St Thomas' NHS Foundation Trust
  • Medical University of Gdansk
  • University of Bordeaux
  • University of Toulouse
  • University of Bonn
  • Hannover Medical School
  • University Medical Center Schleswig-Holstein Campus Kiel
  • Technical University of Munich
  • Justus Liebig University Giessen
  • University of Sheffield
  • Dermatologikum
  • Bern University Hospital
  • National Medical University
  • Erasmus University Medical Center
  • University of Milan
  • Christine Kühne Center for Allergy Research and Education (CK-CARE)
  • University Medical Center Utrecht
  • University of Copenhagen
  • Ludwig-Maximilian University of Munich
  • University of Amsterdam
  • King's College London
  • Larrey Hospital
  • Universitair Ziekenhuis Brussel
  • Vrije Universiteit Brussel (VUB)
  • University of Bern
  • Maggiore Hospital Policlinico
  • Gentofte Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Dermatology and Venereal Diseases
Original languageEnglish
JournalJournal of the European Academy of Dermatology and Venereology
Publication statusE-pub ahead of print - 2019 Jun 23
Publication categoryResearch