Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

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Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. / Sacks, David B.; Arnold, Mark; Bakris, George L.; Bruns, David E.; Horvath, Andrea Rita; Kirkman, M. Sue; Lernmark, Åke; Metzger, Boyd E.; Nathan, David M.

In: Clinical Chemistry, Vol. 57, No. 6, 2011, p. 793-798.

Research output: Contribution to journalDebate/Note/Editorial

Harvard

Sacks, DB, Arnold, M, Bakris, GL, Bruns, DE, Horvath, AR, Kirkman, MS, Lernmark, Å, Metzger, BE & Nathan, DM 2011, 'Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus', Clinical Chemistry, vol. 57, no. 6, pp. 793-798. https://doi.org/10.1373/clinchem.2011.163634

APA

Sacks, D. B., Arnold, M., Bakris, G. L., Bruns, D. E., Horvath, A. R., Kirkman, M. S., Lernmark, Å., Metzger, B. E., & Nathan, D. M. (2011). Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. Clinical Chemistry, 57(6), 793-798. https://doi.org/10.1373/clinchem.2011.163634

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MLA

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Author

Sacks, David B. ; Arnold, Mark ; Bakris, George L. ; Bruns, David E. ; Horvath, Andrea Rita ; Kirkman, M. Sue ; Lernmark, Åke ; Metzger, Boyd E. ; Nathan, David M. / Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. In: Clinical Chemistry. 2011 ; Vol. 57, No. 6. pp. 793-798.

RIS

TY - JOUR

T1 - Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

AU - Sacks, David B.

AU - Arnold, Mark

AU - Bakris, George L.

AU - Bruns, David E.

AU - Horvath, Andrea Rita

AU - Kirkman, M. Sue

AU - Lernmark, Åke

AU - Metzger, Boyd E.

AU - Nathan, David M.

PY - 2011

Y1 - 2011

N2 - BACKGROUND: Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH: An expert committee compiled evidence-based recommendations for the use of laboratory analysis in patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. A draft of the guidelines was posted on the Internet, and the document was modified in response to comments. The guidelines were reviewed by the joint Evidence-Based Laboratory Medicine Committee of the AACC and the National Academy of Clinical Biochemistry and were accepted after revisions by the Professional Practice Committee and subsequent approval by the Executive Committee of the American Diabetes Association. CONTENT: In addition to the long-standing criteria based on measurement of venous plasma glucose, diabetes can be diagnosed by demonstrating increased hemoglobin A(1c) (Hb A(1c)) concentrations in the blood. Monitoring of glycemic control is performed by the patients measuring their own plasma or blood glucose with meters and by laboratory analysis of Hb A(1c). The potential roles of noninvasive glucose monitoring, genetic testing, and measurement of autoantibodies, urine albumin, insulin, proinsulin, C-peptide, and other analytes are addressed. SUMMARY: The guidelines provide specific recommendations based on published data or derived from expert consensus. Several analytes are found to have minimal clinical value at the present time, and measurement of them is not recommended. (C) 2011 American Association for Clinical Chemistry and American Diabetes Association

AB - BACKGROUND: Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH: An expert committee compiled evidence-based recommendations for the use of laboratory analysis in patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. A draft of the guidelines was posted on the Internet, and the document was modified in response to comments. The guidelines were reviewed by the joint Evidence-Based Laboratory Medicine Committee of the AACC and the National Academy of Clinical Biochemistry and were accepted after revisions by the Professional Practice Committee and subsequent approval by the Executive Committee of the American Diabetes Association. CONTENT: In addition to the long-standing criteria based on measurement of venous plasma glucose, diabetes can be diagnosed by demonstrating increased hemoglobin A(1c) (Hb A(1c)) concentrations in the blood. Monitoring of glycemic control is performed by the patients measuring their own plasma or blood glucose with meters and by laboratory analysis of Hb A(1c). The potential roles of noninvasive glucose monitoring, genetic testing, and measurement of autoantibodies, urine albumin, insulin, proinsulin, C-peptide, and other analytes are addressed. SUMMARY: The guidelines provide specific recommendations based on published data or derived from expert consensus. Several analytes are found to have minimal clinical value at the present time, and measurement of them is not recommended. (C) 2011 American Association for Clinical Chemistry and American Diabetes Association

U2 - 10.1373/clinchem.2011.163634

DO - 10.1373/clinchem.2011.163634

M3 - Debate/Note/Editorial

C2 - 21617153

VL - 57

SP - 793

EP - 798

JO - Clinical Chemistry

JF - Clinical Chemistry

SN - 0009-9147

IS - 6

ER -