Expression analysis of a family of developmentally-regulated cytosolic sulfotransferases (SULTs) in Drosophila.

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Abstract

We have compared the amino acid sequence of all four cytosolic sulfotransferases (SULTs) in Drosophila and analyzed their spatial expression patterns during development. Three out of four SULTs show distinct expression activity during embryogenesis, while the 4th SULT shows expression only post-embryonically. st1, st3 and st4 are expressed in non-overlapping expression domains mainly confined to organs of the alimentary canal such as esophagus, malphigian tubules, hindgut, as well as in the tracheal system. All these organs are surrounded by the hemolymph suggesting that Drosophila SULTs exert their function in detoxification of substances upon influx from the hemolymph.

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  • Genetics
Original languageEnglish
Pages (from-to)44-48
JournalHereditas
Volume150
Issue number2-3
Publication statusPublished - 2013
Publication categoryResearch
Peer-reviewedYes

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