Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease.

Research output: Contribution to journalArticle

Abstract

-Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic variants active in and across tissues mediating CAD risk through gene expression.

Details

Authors
  • Hassan Foroughi Asl
  • Husain A Talukdar
  • Alida S D Kindt
  • Rajeev K Jain
  • Raili Ermel
  • Arno Ruusalepp
  • Khanh-Dung H Nguyen
  • Radu Dobrin
  • Dermot F Reilly
  • Heribert Schunkert
  • Nilesh J Samani
  • Ingrid Brænne
  • Jeanette Erdmann
  • Olle Melander
  • Jianlong Qi
  • Torbjörn Ivert
  • Josefin Skogsberg
  • Eric E Schadt
  • Tom Michoel
  • Johan L M Björkegren
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cardiac and Cardiovascular Systems
Original languageEnglish
Pages (from-to)305
JournalCirculation: Cardiovascular Genetics
Volume8
Issue number2
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes