Extracellular traps: An ancient weapon of multiple kingdoms

Research output: Contribution to journalReview article

Abstract

The discovery, in 2004, of extracellular traps released by neutrophils has extended our understanding of the mode of action of various innate immune cells. This fascinating discovery demonstrated the extracellular trapping and killing of various pathogens by neutrophils. During the last decade, evidence has accumulated showing that extracellular traps play a crucial role in the defence mechanisms of various cell types present in vertebrates, invertebrates, and plants. The aim of this review is to summarise the relevant literature on the evolutionary history of extracellular traps used as a weapon in various kingdoms of life.

Details

Authors
Organisations
External organisations
  • University of Veterinary Medicine Hannover
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Immunology in the medical area

Keywords

  • Conserved mechanisms, Defence mechanism, Innate immunity, Neutrophil extracellular traps (NETs), Tree of life
Original languageEnglish
Article number34
JournalBiology
Volume9
Issue number2
Publication statusPublished - 2020
Publication categoryResearch
Peer-reviewedYes