First case of type E wound botulism diagnosed using real-time PCR.
Research output: Contribution to journal › Article
Wound botulism is a growing problem among injecting drug users. The condition is often difficult to diagnose, with laboratory confirmation in only 50% of the cases. Here we present a real-time PCR-based method for the diagnosis of wound botulism caused by Clostridium botulinum. The assay includes an internal amplification control which is amplified simultaneously with the genes encoding neurotoxin types A, B, and E. This method was used to detect the first case of wound botulism in an injecting drug user in Sweden. In addition, to the best of our knowledge, this is the first reported case of wound botulism caused by C. botulinum type E.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Journal of Clinical Microbiology|
|Publication status||Published - 2007|
Related research output
Real-time PCR for diagnosis of botulism and quantification of neurotoxin gene expression in Clostridium botulinumIngrid Artin, 2008, Divison of Medical Microbiology. 157 p.
Research output: Thesis › Doctoral Thesis (compilation)