First-order nociceptive synapses in rat dorsal horn are blocked by an amino acid antagonist
Research output: Contribution to journal › Article
An antagonist to amino acid evoked excitation, γ-d-glutamylglycine (γ-DGG) inhibits, dose-dependently, nociceptive C-fibre evoked field potentials and neuronal discharges in single nociceptive neurons in rat spinal cord. It is concluded that amino acids are possible transmitter substance(s) in nociceptive afferent C-fibres. These results might be useful for development of centrally acting analgesic drugs.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Number of pages||5|
|Publication status||Published - 1986 Aug 6|