From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

Research output: Contribution to journalArticle

Abstract

The objective of this symposium at the First International Congress of Respiratory Biology (ICRB) was to enhance communication between comparative biologists and cancer researchers working on O-2 sensing via the HIF pathway. Representatives from both camps came together on August 13-16, 2006, in Bonn, Germany, to discuss molecular adaptations that occur after cells have been challenged by a reduced (hypoxia) or completely absent (anoxia) supply of oxygen. This brief "critters-to-cancer" survey discusses current projects and new directions aimed at improving understanding of hypoxic signaling and developing therapeutic interventions.

Details

Authors
  • D. Hoogewijs
  • N. B. Terwilliger
  • K. A. Webster
  • J. A. Powell-Coffman
  • S. Tokishita
  • H. Yamagata
  • T. Hankeln
  • T. Burmester
  • K. T. Rytkonen
  • M. Nikinmaa
  • D. Abele
  • K. Heise
  • M. Lucassen
  • J. Fandrey
  • R. H. Maxwell
  • Sven Påhlman
  • T. A. Gorr
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology
Original languageEnglish
Pages (from-to)552-577
JournalIntegrative and Comparative Biology
Volume47
Issue number4
Publication statusPublished - 2007
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Molecular Medicine (013031200)