Frontotemporal dementia and its subtypes: a genome-wide association study.

Research output: Contribution to journalArticle

Abstract

Frontotemporal dementia (FTD) is a complex disorder characterised by a broad range of clinical manifestations, differential pathological signatures, and genetic variability. Mutations in three genes-MAPT, GRN, and C9orf72-have been associated with FTD. We sought to identify novel genetic risk loci associated with the disorder.

Details

Authors
  • Raffaele Ferrari
  • Dena G Hernandez
  • Michael A Nalls
  • Jonathan D Rohrer
  • Adaikalavan Ramasamy
  • John B J Kwok
  • Carol Dobson-Stone
  • William S Brooks
  • Peter R Schofield
  • Glenda M Halliday
  • John R Hodges
  • Olivier Piguet
  • Lauren Bartley
  • Elizabeth Thompson
  • Eric Haan
  • Isabel Hernández
  • Agustín Ruiz
  • Mercè Boada
  • Barbara Borroni
  • Alessandro Padovani
  • Carlos Cruchaga
  • Nigel J Cairns
  • Luisa Benussi
  • Giuliano Binetti
  • Roberta Ghidoni
  • Gianluigi Forloni
  • Daniela Galimberti
  • Chiara Fenoglio
  • Maria Serpente
  • Elio Scarpini
  • Jordi Clarimón
  • Alberto Lleó
  • Rafael Blesa
  • Karin Nilsson
  • Christer Nilsson
  • Ian R A Mackenzie
  • Ging-Yuek R Hsiung
  • David M A Mann
  • Jordan Grafman
  • Christopher M Morris
  • Johannes Attems
  • Timothy D Griffiths
  • Ian G McKeith
  • Alan J Thomas
  • P Pietrini
  • Edward D Huey
  • Eric M Wassermann
  • Atik Baborie
  • Evelyn Jaros
  • Michael C Tierney
  • Pau Pastor
  • Cristina Razquin
  • Sara Ortega-Cubero
  • Elena Alonso
  • Robert Perneczky
  • Janine Diehl-Schmid
  • Panagiotis Alexopoulos
  • Alexander Kurz
  • Innocenzo Rainero
  • Elisa Rubino
  • Lorenzo Pinessi
  • Ekaterina Rogaeva
  • Peter St George-Hyslop
  • Giacomina Rossi
  • Fabrizio Tagliavini
  • Giorgio Giaccone
  • James B Rowe
  • Johannes C M Schlachetzki
  • James Uphill
  • John Collinge
  • Simon Mead
  • Adrian Danek
  • Vivianna M Van Deerlin
  • Murray Grossman
  • John Q Trojanowski
  • Julie van der Zee
  • William Deschamps
  • Tim Van Langenhove
  • Marc Cruts
  • Christine Van Broeckhoven
  • Stefano F Cappa
  • Isabelle Le Ber
  • Didier Hannequin
  • Véronique Golfier
  • Martine Vercelletto
  • Alexis Brice
  • Benedetta Nacmias
  • Sandro Sorbi
  • Silvia Bagnoli
  • Irene Piaceri
  • Jørgen E Nielsen
  • Lena E Hjermind
  • Matthias Riemenschneider
  • Manuel Mayhaus
  • Bernd Ibach
  • Gilles Gasparoni
  • Sabrina Pichler
  • Wei Gu
  • Martin N Rossor
  • Nick C Fox
  • Jason D Warren
  • Maria Grazia Spillantini
  • Huw R Morris
  • Patrizia Rizzu
  • Peter Heutink
  • Julie S Snowden
  • Sara Rollinson
  • Anna Richardson
  • Alexander Gerhard
  • Amalia C Bruni
  • Raffaele Maletta
  • Francesca Frangipane
  • Chiara Cupidi
  • Livia Bernardi
  • Maria Anfossi
  • Maura Gallo
  • Maria Elena Conidi
  • Nicoletta Smirne
  • Rosa Rademakers
  • Matt Baker
  • Dennis W Dickson
  • Neill R Graff-Radford
  • Ronald C Petersen
  • David Knopman
  • Keith A Josephs
  • Bradley F Boeve
  • Joseph E Parisi
  • William W Seeley
  • Bruce L Miller
  • Anna M Karydas
  • Howard Rosen
  • John C van Swieten
  • Elise G P Dopper
  • Harro Seelaar
  • Yolande A L Pijnenburg
  • Philip Scheltens
  • Giancarlo Logroscino
  • Rosa Capozzo
  • Valeria Novelli
  • Annibale A Puca
  • Massimo Franceschi
  • Alfredo Postiglione
  • Graziella Milan
  • Paolo Sorrentino
  • Mark Kristiansen
  • Huei-Hsin Chiang
  • Caroline Graff
  • Florence Pasquier
  • Adeline Rollin
  • Vincent Deramecourt
  • Florence Lebert
  • Dimitrios Kapogiannis
  • Luigi Ferrucci
  • Stuart Pickering-Brown
  • Andrew B Singleton
  • John Hardy
  • Parastoo Momeni
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Neurology
Original languageEnglish
Pages (from-to)686-699
JournalLancet Neurology
Volume13
Issue number7
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Psychogeriatrics (013304000)