G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.

Research output: Contribution to journalArticle

Abstract

G protein-coupled estrogen receptor 1 (GPER1), previously named GPR30, is a membrane receptor reported to mediate nongenomic estrogen responses. We investigated if GPER1 expression correlates with any clinicopathologic variables and distant disease-free survival (DDFS) in patients with breast cancer, if any prognostic impact of the receptor is dependent on estrogen receptor-α (ER-α) status, and if the receptor impacts apoptotic signaling in ER-positive breast cancer cells.

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  • Cancer and Oncology
Original languageEnglish
Pages (from-to)1681-1692
JournalClinical Cancer Research
Volume19
Issue number7
Publication statusPublished - 2013
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Cancer Epidemiology (013007100), Oncology, MV (013035000), Department of Experimental Medical Science (013210000), Cardiology (013230026), Pathology, (Lund) (013030000), Drug Target Discovery (013212045)

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