Gallium phosphide nanowires as a substrate for cultured neurons

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Abstract

Dissociated sensory neurons were cultured on epitaxial gallium phosphide (GaP) nanowires grown vertically from a gallium phosphide surface. Substrates covered by 2.5 mu m long, 50 nm wide nanowires supported cell adhesion and axonal outgrowth. Cell survival was better on nanowire substrates than on planar control substrates. The cells interacted closely with the nanostructures, and cells penetrated by hundreds of wires were observed as well as wire bending due to forces exerted by the cells.

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  • Nano Technology
Original languageEnglish
Pages (from-to)2960-2965
JournalNano Letters
Volume7
Issue number10
Publication statusPublished - 2007
Publication categoryResearch
Peer-reviewedYes