Gonococci cause immunosuppression by engaging a coinhibitory receptor on T lymphocytes

Research output: Contribution to journalLetter

Abstract

Gonococci that bind the coinhibitory receptor CEACAM1 appear to down-regulate the activation and proliferation of CD4+ T cells. Such infection-induced immunosuppression helps explain why there is little specific immune response associated with gonococcal disease.

Details

Authors
  • Staffan Normark
  • Barbara Albiger
  • Ann-Beth Jonsson
External organisations
  • External Organization - Unknown
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Microbiology in the medical area
Original languageEnglish
Pages (from-to)210-211
JournalNature Immunology
Volume3
Issue number3
Publication statusPublished - 2002
Publication categoryResearch
Peer-reviewedYes
Externally publishedYes