Group A streptococci are protected from amoxicillin-mediated killing by vesicles containing β-lactamase derived from Haemophilus influenzae.
Research output: Contribution to journal › Article
Group A streptococci (GAS) cause, among other infections, pharyngotonsillitis in children. The species is frequently localized with the Gram-negative respiratory pathogens non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis, which both produce outer membrane vesicles (OMVs). The aim of this study was to investigate whether OMVs isolated from NTHi contain functional β-lactamase and whether the OMVs hydrolyse amoxicillin and thus protect GAS from killing by the antibiotic.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Journal of Antimicrobial Chemotherapy|
|Publication status||Published - 2014|
No data available
Related research output
2013, Medical Microbiology, Lund University.
Research output: Thesis › Doctoral Thesis (compilation)