Hepatocellular carcinoma associated with arteriohepatic dysplasia in a 4-year-old girl

Research output: Contribution to journalArticle

Abstract

Hepatocellular carcinoma and obliterated hepatic bile duct were found at postmortem examination in a 4-year-old girl with arteriohepatic dysplasia (Alagille's syndrome). AFP level was extremely high. Liver cirrhosis was present on percutaneous needle biopsy 9 months before she succumbed in progressive liver failure. Episodes of repeated gastrointestinal, life-threatening hemorrhages occurred during the last 6 months of her life. Histopathologic findings of the eyes were documented at autopsy.

Details

Authors
  • Albert Békássy
  • Stanislaw Garwicz
  • Thomas Wiebe
  • Inga Hägerstrand
  • Ove A Jensen
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Pediatrics

Keywords

  • Alagille's syndrome, child, hepatic carcinoma, liver cirrhosis, biliary atresia, autopsy, histopathology, eyes, liver, AFP
Original languageEnglish
Pages (from-to)78-83
JournalMedical and Pediatric Oncology
Volume20
Issue number1
Publication statusPublished - 1992
Publication categoryResearch
Peer-reviewedYes