Heterocycles of biological importance: Part 7. Synthesis of biologically active pyrimido[2,1-b]benzothiazoles from acetylenic acids and 2-aminobenzothiazoles

Research output: Contribution to journalArticle

Abstract

Conjugate addition of the imino nitrogen of 2-aminobenzothiazoles 1 to the alkyne beta-carbon atom of acetylenic acids 2 followed by ring closure gives rise to novel 2H-pyrimido[2,1-b]-benzothiazol-2-ones in good yield.

Details

Authors
  • H Wahe
  • JT Mbafor
  • AE Nkengfack
  • ZT Fomum
  • RA Cherkasov
  • Olov Sterner
  • D Doepp
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry

Keywords

  • fused nitrogen heterocycles, Michael addition, amidines, cyclocondensation
Original languageEnglish
Pages (from-to)107-114
JournalArkivoc
Volume2003
Issue numberXV
Publication statusPublished - 2003
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)